Table. 2. Compounds produced by lactic acid bacteria and their individual minimal inhibitory concentration (MIC) values against yeast, mould and bacteria as well as the reported production concentration in LAB. The concentration produced are highly dependent on the conditions used and should only be considered as an indicator (Siedler et al., 2019)

Compound MIC yeast (mM) MIC mould (mM) MIC bac3) (mM) Reference Produced (mM) Reference
Lactic acid 278 274-405 2-11 Leon Pelaez et al., 2012;Narendranath et al., 2001;Ostling et al., 1993 55 Le Lay et al., 2016
Acetic acid 100 38-41;808.3 0.5-14 Corsetti et al., 1998;Leon Pelaez et al., 2012;Narendranath et al., 2001;Ostling et al., 1993;Stratford et al., 2009 5-40 Aunsbjerg et al., 2015Corsetti et al., 1998;Le Lay et al., 2016
Benzoic acid 10 1.271) Arroyo-Lopez et al., 2008 0.19 Urbiene & Leskauskaite, 2006;Yu et al., 2016
Azelacid acid 4.510.6-21.3 Farmery et al., 1994;Maple et al., 1992 0.01 Le Lay et al., 2016
Succinic acid 200-500 Schwenninger et al., 2008 29-300 Ozcelik et al., 2016;Schwenninger et al., 2008
Propionic acid 8.1 Corsetti et al., 1998 54 Zhang et al., 2010
Formic acid 21-43 19.5 0.1-1.5 Corsetti et al., 1998;Lastauskiene et al., 2014;Ostling et al., 1993 1.5-27 Corsetti et al., 1998;Ozcelik et al., 2016;Rizzello et al., 2011
Ethanol 434 Berni & Scaramuzza, 2013 80 Elshaghabee et al., 2016
Diacetyl 1.45-2.9 0.005-0.7 0.005-0.011 Aunsbjerg et al., 2015 0.15-0.7 Aunsbjerg et al., 2015
Hydrogen peroxide 4.4-80 1-2 Brudzynski et al., 2011;Larsen et al., 1995 0.0006 Le Lay et al., 2016
Reuterin/acrolein 8-50 Cleusix et al., 2007
Reutericyclin 0.3-2.81) Ganzle et al., 2003 141) Ganzle et al., 2003
Cyclo (L-Phe-L-Pro) 0.08 Strom et al., 2002
3-Phenyllactic acid 50-5003), 55 Schwenninger et al., 2008;Strom et al., 2002 <70.57 Schwenninger et al., 2008;Valerio et al., 2004
4-Hdroxyphenyllactic acid 50-5002) Schwenninger et al., 2008 <7 Schwenninger et al., 2008
3-Hydroxy fatty acids <0.46 <0.46 Sjogren et al., 2003 0.009 Sjogren et al., 2003
Indolelactic acid 24 Honore et al., 2016 0.02 Honore et al., 2016
2-Hydroxy-(4-methylthio)butanoic acid 66 Honore et al., 2016 0.029 Honore et al., 2016
2-Hydroxy-3-methylbutanoic acid 42 Honore et al., 2016 0.2 Honore et al., 2016
2-Hydroxy-4-methylbutanoic acid 38 Honore et al., 2016 0.49 Honore et al., 2016
δ-Dodecalactone 3.2-4.2 1.7-3.2 3.9-31 Yang et al., 2011
μM.
pH-dependent.
Bacteria.