Table 7 A clinical investigation of the ophthalmic findings affected by the 90-day oral administration of 7%-GNANA, a test substance to the male and female rats (n=10)

Sites Findings Groups (mg/kg/day)b)
G1% G2 G3 G4
Male Female Male Female Male Female Male Female
Left eye Normal 0 / 5a) 0 / 5a) 0 / 5 0 / 5 0 / 5 0 / 5 0 / 5 0 / 5
Right eye Normal 0 / 5 0 / 5 0 / 5 0 / 5 0 / 5 0 / 5 0 / 5 0 / 5
a) Number of animals with the finding / Number of animals examined
%: Control group (G1), Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day), High-dose group (G4: 5,000 mg/10 mL/day)
The data shown represent mean±S.D. (n=10).