Table 4 Investigation results of clinical signs through the autopsy after the 90-day oral administration of 7%-GNANA, a test substance to the male and female rats (n=10)

Days	Signs	Groups (mg/kg/day)^b)
		G1^%,a)		G2		G3		G4
		Male	Female	Male	Female	Male	Female	Male	Female
0	No finding	0 / 10^a)	0 / 10^a)	0 / 10^a)	0 / 10^a)	0 / 10^a)	0 / 10 ^a)	0 / 10^a)	0 / 10^a)
1~7	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
8~14	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
15~21	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
22~28	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
29~35	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
36~42	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
43~49	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
50~56	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
57~63	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
64~70	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
71~77	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
78~84	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
85~89	No finding	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10	0 / 10
90	Terminal sacrifice	10 / 10	10 / 10	10 / 10	10 / 10	10 / 10	10 / 10	10 / 10	10 / 10

^a) Number of animals with the sign / Number of animals examined.
%: Control group (G1) Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day), High-dose group (G4: 5,000 mg/10 mL/day)