Table 6 An assessment of the food consumption changes affected by the 90-day oral administration of 23%-GNANA, a test substance to the male and female rats (n=10)

Weeks	Groups (mg/kg/day)a)
	G1 (0)%		G2 (1,250)		G3 (2,500)		G4 (5,000)
	Male	Female	Male	Female	Male	Female	Male	Female
0	21.7±1.16	16.9±1.20	21.7±1.13	16.9±2.12	21.9±1.21	16.3±0.75	21.7±1.01	16.0±0.98*
1	21.0±0.85	15.2±0.91	21.6±0.98	14.5±0.85	21.5±0.58	14.7±1.24	20.1±1.26	13.7±0.92
2	22.4±1.22	15.9±0.76	22.9±1.30	14.5±1.07	22.5±0.51	14.5±1.17	21.8±1.02	14.2±0.61
3	22.6±1.02	16.9±1.14	23.9±1.45	16.0±0.63	23.6±0.91	15.7±1.51	22.6±1.35	14.9±0.96
4	23.2±1.60	17.0±1.93	23.9±1.46	16.5±1.65	23.6±0.70	17.3±2.30	22.7±1.36	16.0±1.50
5	22.7±1.69	17.2±0.87	23.9±1.52	15.7±1.09	23.9±0.56	15.5±1.17	23.1±1.77	14.4±0.90
6	23.7±1.06	17.3±1.20	24.4±1.64	16.9±1.29	24.0±0.89	15.9±1.62	23.6±1.71	14.0±0.75
7	23.6±1.49	17.7±1.32	24.6±1.57	17.1±0.82	24.9±1.01	17.0±1.15	24.2±1.89	14.4±0.40
8	23.9±1.54	16.9±1.79	24.7±1.23	16.2±2.04	24.8±1.43	17.6±1.52	23.7±1.72	14.7±0.43
9	23.5±1.68	15.6±1.66	24.4±1.59	15.5±1.18	24.7±1.01	15.0±1.13	22.6±1.69	14.3±0.72
10	23.2±1.58	16.5±1.31	24.1±1.79	16.8±1.99	24.2±0.98	15.0±2.40	22.6±1.55	15.8±2.01
11	23.7±1.37	16.4±1.53	24.0±1.71	16.3±1.19	24.0±1.19	15.5±1.40	22.4±1.20	14.1±0.65
12	23.4±1.37	17.2±1.30	23.9±1.85	16.5±1.87	23.7±1.46	15.3±2.90	22.1±1.55	13.1±0.98
13	23.5±1.84	15.6±1.29	23.8±1.93	16.4±2.50	23.2±1.49	15.5±1.94	21.2±1.65	13.5±0.64
Average	23.0±1.27	16.6±1.01*	23.7±1.45	16.1±1.12	23.6±0.81	15.8±1.05	22.5±1.39	14.5±0.37

^*: Represents a significant difference at p<0.05 level compared with the vehicle control
%: Control group (G1), Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day), High-dose group (G4: 5,000 mg/10 mL/day)